PD-1 & TIGIT & TIM3

Nomenclature
Cat. NO.ASHU-190029
Strain State

Gene Summary:

Synonyms
NCBI ID/m/o/mouse-model-20200122_137.jpg
MGI ID/m/o/mouse-model-20200122_137.jpg
Ensembl ID
Human OrthologsOff-shelf mouse catalog offers >100 humanized mouse models, includes PD-1 & TIGIT & TIM3, target PD-1, Pdc1, Ly101|Vstm3|Tim3, TIM-3, Timd3 for your immunotherapy preclinical research.

Description:

PD-1 Knock-in Strategy

\"PD1/TIGIT/TIM3

Figure 1. Gene knock-in strategy to engineer a humanized PD-1 (PD-1-HU) mouse model. The endogenous mouse Pdcd1 gene was replaced by insertion of the full length protein coding sequence for the human PDCD1 (PD-1) gene into the ATG position of mPdcd1