Immunotherapy
LAG3 & CTLA4
LAG3 & CTLA4
Nomenclature
B6.129 - Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Asc
Cat. NO.ASHU-190018
Strain State
Gene Summary:
| Synonyms | Ly66, CD223, LAG-3; Cd152, Ly-56, Ctla-4 |
| NCBI ID | 16768; 12477 |
| MGI ID | 106588; 88556 |
| Ensembl ID | ENSMUSG00000030124; ENSMUSG00000026011 |
| Human Orthologs | LAG3; CTLA4 |
Research Application:
Description:
This LAG3 and CTLA4 double Knock-in strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.