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PD-1 & CD40
PD-1 & CD40
Nomenclature
PD-1 & CD40
Cat. NO.ASHU-190017
Strain State
Gene Summary:
| Synonyms | Humanized |
| NCBI ID | |
| MGI ID | |
| Ensembl ID | |
| Human Orthologs |
Research Application:
Description:
Humanized Strategy
Strategy for Generating Humanized PD-1 (ASHU-00015) Mouse Model
Strategy for Generating Humanized CD40 (ASHU-00076) Mouse Model
Validation Data: PD-1
Figure 1. Expression of PD-1 in the activated spleen lymphocytes of humanized PD-1 Homozygous mice is detected by FACS.
Figure 2. In vivo anti-tumor effect of an anti-human PD-1 antibody in a humanized mouse model of PD-1. Anti-human-PD-1 drugs significantly inhibited the growth of MC38 tumors in PD-1 mice