CTLA4 & ICOS

Nomenclature
C57BL/6J - Ctla4em1(hCTLA4) Icosem1(hICOS)/Asc
Cat. NO.ASHU-190016
Strain State

Gene Summary:

SynonymsCd152, Ly-56, Ctla-4; AILIM, CCLP, CRP-1, H4, Ly115
NCBI ID12477; 54167
MGI ID88556; 1858745
Ensembl IDENSMUSG00000026011; ENSMUSG00000026009
Human OrthologsCTLA4; ICOS

Research Application:

Immunotherapy

Description:

This CTLA4 and ICOS double Knock-in strain is established by crossing CTLA4-HU and ICOS-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.