PD-L1 & GITR

Nomenclature
C57BL/6J - Cd274em1(hPD - L1)Tnfrsf18em1(hTNFRSF18)/Asc
Cat. NO.ASHU-190015
Strain State

Gene Summary:

SynonymsB7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik; AITR, Gitr
NCBI ID60533;21936
MGI ID1926446; 894675
Ensembl IDENSMUSG00000016496; ENSMUSG00000041954
Human OrthologsCD274; TNFRSF18

Research Application:

Immunotherapy

Description:

This PD-L1 and GITR double Knock-in strain is established by crossing PD-L1-HU and GITR-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.