Immunotherapy, cancer research, drug screening
PD-L1 & CD40
PD-L1 & CD40
Nomenclature
C57BL/6-Cd274em1(hPD - L1) Cd40em1(hCD40)/Asc
Cat. NO.ASHU-18024
Strain State
Gene Summary:
| Synonyms | B7h1, Pdl1, Pdcd1l1, Pdcd1lg1, A530045L16Rik, IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936 |
| NCBI ID | 60533, 21939 |
| MGI ID | 1926446, 88336 |
| Ensembl ID | ENSMUSG00000016496, ENSMUSG00000017652 |
| Human Orthologs | CD274, CD40 |
Research Application:
Description:
This PD-L1 and CD40 double knockin strain is established by crossing PD-L1-HU and CD40-HU mice together. These double double knockin mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations.