Immunotherapy, cancer research, drug screening
PD-1 & CD3E
PD-1 & CD3E
Nomenclature
C57BL/6-Pdcd1em1(hPDCD1) Cd3eem1(hCD3E)/Asc
Cat. NO.ASHU-18021
Strain State
Gene Summary:
| Synonyms | Ly101, CD3, T3e, AI504783, CD3epsilon |
| NCBI ID | 18566, 12501 |
| MGI ID | 104879, 88332 |
| Ensembl ID | ENSMUSG00000026285, ENSMUSG00000032093 |
| Human Orthologs | PDCD1, CD3E |
Research Application:
Description:
This PD-1 and CD3e double knockin strain is established by crossing PD-1-HU and CD3e-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.