Immunotherapy, cancer research, drug screening
CTLA4 & 4-1BB
CTLA4 & 4-1BB
Nomenclature
C57BL/6 - Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Asc
Cat. NO.ASHU-18020
Strain State
Gene Summary:
| Synonyms | Cd152, Ly-56, Ctla-4, 4-1BB, A930040I11Rik, Cd137, CDw137, ILA, Ly63 |
| NCBI ID | 12477, 21942 |
| MGI ID | 88556, 1101059 |
| Ensembl ID | ENSMUSG00000026011, ENSMUSG00000028965 |
| Human Orthologs | CTLA4, TNFRSF9 |
Research Application:
Description:
This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations.