Humanized
PD-L1 & LAG3
PD-L1 & LAG3
Nomenclature
ENSMUSG00000016496, ENSMUSG00000030124
Cat. NO.ASHU-00137
Strain State
Gene Summary:
| Synonyms | C57BL/6J - Cd274<sup>em1(hPD - L1)</sup>Lag3<sup>tm1(hLAG3)/Asc</sup> |
| NCBI ID | C57BL/6 |
| MGI ID | 60533, 16768 |
| Ensembl ID | 1926446, 106588 |
| Human Orthologs | Humanized |
Research Application:
Description:
Humanized Strategy
Strategy for Generating Humanized PD-L1 (ASHU-00062) Mouse Model
Strategy for Generating Humanized LAG3 (ASHU-00049) Mouse Model
Validation Data
Figure 1. Splenocytes from homozygous hPDL1/hLAG3 mice were analyzed by flow cytometry after activation. The mPDL1+ and mLAG3+ cells were detectable in wild type (WT) C57BL/6 mice