Immunotherapy, cancer research, drug screening
CD3E
CD3E
Nomenclature
C57BL/6-Cd3eem1(hCD3E)/Asc
Cat. NO.ASHU-00114
Strain State
Gene Summary:
| Synonyms | CD3, T3e, AI504783, CD3epsilon |
| NCBI ID | 12501 |
| MGI ID | 88332 |
| Ensembl ID | ENSMUSG00000032093 |
| Human Orthologs | CD3E |
Research Application:
Description:
Humanized Gene Knock-in Strategy
Validation Data
Figure 1. The expression of human CD3E in the peripheral blood cells derived from heterozygous or homozygous humanized mice was confirmed by FACS.
Figure 2. Detection of T cell subsets in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.
Figure 3. Detection of B and NK cells in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.
Figure 4. In vitro T cell activation with heterozygous or homozygous CD3E humanized mice.
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