PD-L1 & CTLA4
PD-L1 & CTLA4
PD-L1 & CTLA4
Nomenclature
88556, 1926446
Cat. NO.ASHU-00102
Strain State
Gene Summary:
| Synonyms | ENSMUSG00000026011, ENSMUSG00000016496 |
| NCBI ID | CTLA4, CD274 |
| MGI ID | C57BL/6 |
| Ensembl ID | 12477, 60533 |
| Human Orthologs | Immunotherapy, cancer research, drug screening |
Research Application:
Description:
Generation Strategy
Strategy for Generating Humanized PD-L1 (ASHU-00062) Mouse Model
Strategy for Generating Humanized CTLA4 (ASHU-00014) Mouse Model
Validation Data
Figure 1. Splenocytes from homozygous hPD-L1/hCTLA4 mice were analyzed by flow cytometry after activation. The murine Pd-l1 (mPD-L1) and Ctla4 (mCTLA4) positive cells were detectable in wild type (WT) C57BL/6 mice