Immunotherapy, cancer research, drug screening
CTLA4
CTLA4
Nomenclature
C57BL/6 - Ctla4em1(hCTLA4)/Asc
Cat. NO.ASHU-00014
Strain State
Gene Summary:
| Synonyms | Cd152, Ly-56, Ctla-4 |
| NCBI ID | 12477 |
| MGI ID | 88556 |
| Ensembl ID | ENSMUSG00000026011 |
| Human Orthologs | CTLA4 |
Research Application:
Description:
Humanized Gene Knock-in Strategy
Flow Cytometry Validation of hCTLA4 Expression in Splenocytes from Humanized CTLA4 Mice Stimulated with mCD3/CD28 Antibody for 72 hours
(Data in partnership with collaborators)
In Vivo Validation of hCTLA4 Expression in a MC38 Colon Cancer Model of the Humanized CTLA4 Mouse Model
(Data in partnership with collaborators)
(Data in partnership with collaborators)
Analysis of Tumor-infiltrating Lymphocytes (TILS) in a MC38 Colon Cancer Model of the Humanized CTLA4 Mouse Model
(Data in partnership with collaborators)
Analysis of Spleen T Cells in a MC38 Colon Cancer Model of the Humanized CTLA4 Mouse Model
(Data in partnership with collaborators)
Analysis of T Cells in Tumor Draining Lymph Nodes of Humanized CTLA4 Mouse Model
(Data in partnership with collaborators)