Casp8-CKO

Nomenclature
C57BL/6J-Casp8em1(flox)Asc
Cat. NO.ASCKO-190003
Strain State

Gene Summary:

SynonymsMACH; Mch5; FLICE; CASP-8
NCBI ID12370
MGI ID1261423
Ensembl IDENSMUSG00000026029
Human OrthologsCASP8

Research Application:

Immunotherapy

Description:

These Casp8 flox mice possess loxP sites flanking exons 4 CRISPR/Cas mediated recombination. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.