Immunotherapy
Trpv2-CKO
Trpv2-CKO
Nomenclature
B6.129-Trpv2tm1(flox)Asc
Cat. NO.ASCKO-00023
Strain State
Gene Summary:
| Synonyms | OTRPC2, Vrl1, VRL-1 |
| NCBI ID | 22368 |
| MGI ID | 1341836 |
| Ensembl ID | ENSMUSG00000018507 |
| Human Orthologs | TRPV2 |
Research Application:
Description:
These Trpv2 gene flox mice can be used to abtain tissue specific knockout Trpv2 mice when cross with Cre transgenic mice. Mice homozygous for a conventional knock-out allele exhibit impaired macrophage migration, binding, and phagocytosis with increased susceptiblity and mortality following bacterial infection.